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Article

Implication of Candida parapsilosis FKS1 and FKS2 mutations in reduced echinocandin susceptibility.

Antimicrobial agents and chemotherapy - 1 Jan 2015

Martí-Carrizosa M, Sánchez-Reus F, March F, Cantón E, Coll P

Abstract excerpt

We evaluated FKS1 and FKS2 mutations in Candida parapsilosis bloodstream isolates and correlated them with the echinocandin MIC values determined by guidelines in CLSI document M27-A3 and the YeastOne panel. All mutations detected were outside hot spot (HS) regions. The F1386S mutation detected in an isolate that was resistant by the YeastOne panel but not by the M27-A3 guidelines might be implicated in...

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Identifiers

PMID: 25779577
DOI: 10.1128/AAC.04922-14
PMCID: PMC4432215

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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