Article
Association between HLA-B Alleles and Carbamazepine-Induced Maculopapular Exanthema and Severe Cutaneous Reactions in Thai Patients.
Journal of immunology research - 1 Jan 2018
Sukasem Chonlaphat, Chaichan Chonlawat, Nakkrut Thapanat, Satapornpong Patompong, Jaruthamsophon Kanoot, Jantararoungtong Thawinee, Koomdee Napatrupron, Sririttha Suthida, Medhasi Sadeep, Oo-Puthinan Sarawut, Rerkpattanapipat Ticha, Klaewsongkram Jettanong, Rerknimitr Pawinee, Tuchinda Papapit, Chularojanamontri Leena, Tovanabutra Napatra, Puangpetch Apichaya, Aekplakorn Wichai
Abstract excerpt
The HLA-B∗15:02 allele has been reported to have a strong association with carbamazepine-induced Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) in Thai patients. The HLA-B alleles associated with carbamazepine-induced maculopapular exanthema (MPE) and the drug reaction with eosinophilia and systemic symptoms (DRESS) among the Thai population have never been reported. The aim of the present study...
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