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Dapsone-induced severe cutaneous adverse drug reactions are strongly linked with HLA-B*13: 01 allele in the Thai population.

Pharmacogenetics and genomics - 1 Dec 2017

Tempark Therdpong, Satapornpong Patompong, Rerknimitr Pawinee, Nakkam Nontaya, Saksit Niwat, Wattanakrai Penpun, Jantararoungtong Thawinee, Koomdee Napatrupron, Mahakkanukrauh Ajanee, Tassaneeyakul Wichittra, Suttisai Sumitra, Pratoomwun Jirawat, Klaewsongkram Jettanong, Rerkpattanapipat Ticha, Sukasem Chonlaphat

Abstract excerpt

OBJECTIVES: A previous publication in Chinese leprosy patients showed that the HLA-B*13:01 allele is a strong genetic marker for dapsone-induced drug hypersensitivity reactions, however there are no data describing whether HLA-B*13:01 is a valid marker for prediction of dapsone-induced drug hypersensitivity reactions in other ethnicities or nonleprosy patients. The aim of this study is to investigate whether...

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PMID: 28885988
DOI: 10.1097/FPC.0000000000000306

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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