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Genetic Diversity of HLA Class I and Class II Alleles in Thai Populations: Contribution to Genotype-Guided Therapeutics

27 Feb 2020

Abstract excerpt

Human leukocyte antigen (HLA) class I and II alleles encodes several molecules that play role in the human immune system. There were found the association of HLA alleles and drug-induced cutaneous adverse reactions. The aim of this study was to investigate HLA class I and II alleles distribution in five regions of Thailand and to explore the relation of pharmacogenetic markers. HLA-A, -B, –C, -DRB1, -DQA1 and...

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PMID: 32180714
DOI: 10.3389/fphar.2020.00078

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