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Article

A direct interaction between two Restless Legs Syndrome predisposing genes: MEIS1 and SKOR1.

Scientific reports - 15 Aug 2018

Catoire Helene, Sarayloo Faezeh, Mourabit Amari Karim, Apuzzo Sergio, Grant Alanna, Rochefort Daniel, Xiong Lan, Montplaisir Jacques, Earley Christopher J, Turecki Gustavo, Dion Patrick A, Rouleau Guy A

Abstract excerpt

Restless Legs syndrome (RLS) is a common sleep disorder for which the genetic contribution remains poorly explained. In 2007, the first large scale genome wide association study (GWAS) identified three genomic regions associated with RLS. MEIS1, BTBD9 and MAP2K5/SKOR1 are the only known genes located within these loci and their association with RLS was subsequently confirmed in a number of follow up GWAS....

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Source

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Identifiers

PMID: 30111810
DOI: 10.1038/s41598-018-30665-6
PMCID: PMC6093889

Genes

SKOR1
MEIS1
BTBD9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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