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Article

ADAMTS-13 activity and ischemic heart disease: a Mendelian randomization study.

Journal of thrombosis and haemostasis : JTH - 1 Nov 2018

Schooling C M, Luo S, Johnson G

Abstract excerpt

Essentials Cardiovascular disease remains the leading cause of global mortality despite progress in control. We assessed the role of ADAMTS-13 in ischemic heart disease using Mendelian randomization. Genetically instrumented ADAMTS-13 activity reduced ischemic heart disease. Therapeutics targeting ADAMTS-13 activity could perhaps be repurposed in ischemic heart disease. BACKGROUND: Despite great progress in the...

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Identifiers

PMID: 30099840
DOI: 10.1111/jth.14267

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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