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Article

ADAMTS13 Gene Polymorphisms and Coronary Artery Disease Risk, Long-Term Survival, and Risk Factor Profile.

Genes - 25 Apr 2026

Wrona Justyna, Balcerzyk-Matić Anna, Mizia-Stec Katarzyna, Filipecki Artur, Krauze Jolanta, Niemiec Paweł

Abstract excerpt

BACKGROUND: ADAMTS13 is a protein that cleaves large multimers of von Willebrand factor, thereby limiting platelet aggregation and adhesion and regulating thrombogenesis. Research findings suggest a possible association between low ADAMTS13 levels and an increased risk of cardiovascular events, and its activity may be influenced by polymorphic variants of the ADAMTS13 gene. METHODS: The study group included 259...

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Source

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Identifiers

PMID: 42194965
DOI: 10.3390/genes17050508
PMCID: PMC13205630

Genes

ADAMTS13
CAD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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