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Article

Investigating the association between serum ADAM/ADAMTS levels and bone mineral density by mendelian randomization study.

BMC genomics - 19 Jul 2023

Lv Xin, Lin Yuhong, Zhang Zhilei, Li Bo, Zeng Ziliang, Jiang Xu, Zhao Qiancheng, Li Wenpeng, Wang Zheyu, Yang Canchun, Yan Haolin, Wang Qiwei, Huang Renyuan, Hu Xumin, Gao Liangbin

Abstract excerpt

PURPOSE: A Disintegrin and Metalloproteinase (ADAM) and A Disintegrin and Metalloproteinase with Thrombospondin Motif (ADAMTS) have been reported potentially involved in bone metabolism and related to bone mineral density. This Mendelian Randomization (MR) analysis was performed to determine whether there are causal associations of serum ADAM/ADAMTS with BMD in rid of confounders. METHODS: The genome-wide summary...

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Identifiers

PMID: 37468870
DOI: 10.1186/s12864-023-09449-4
PMCID: PMC10354922

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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