Article
Association of characteristics of HBV quasispecies with hepatitis B surface antigen seroconversion after pegylated interferon-α-2a treatment in child patients.
Antiviral therapy - 1 Jan 2018
Yang Juncheng, Yang Guifeng, He Haitang, Ning Lu, Liu Zhihua, Fu Qunfang, Chen Haitao, Deng Haohui, Wang Zhanhui, Luo Kangxian
Abstract excerpt
BACKGROUND: The correlation between hepatitis B surface antigen (HBsAg) seroconversion and the characteristics of HBV quasispecies (QS) before and during pegylated interferon-α-2a (PEG-IFN-α-2a) treatment in hepatitis B e antigen (HBeAg)-positive chronic hepatitis B (CHB) children has not yet been reported. METHODS: 35 patients, including 18 HBsAg seroconverters (SS) and 17 non-seroconverters (SN), were enrolled....
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