Article
Intra-host diversity of hepatitis B virus during mother-to-child transmission: the X gene may play a key role in virus survival in children after transmission.
Archives of virology - 1 Jun 2020
Li Yanjie, Shen Chenguang, Yang Liuqing, Yang Yang, Wang Miao, Li Shanqin, Chen Feng, Yang Min, Peng Ling, Ma Jinmin, Duan Zhongping, Li Liqiang, Liu Yingxia
Abstract excerpt
Mother-to-child transmission of hepatitis B virus (HBV) is the main route of transmission in Asia, and characterization of HBV quasispecies is needed to further understand virus evolution and adaptation. To understand changes in HBV during mother-to-child transmission, we enrolled nine pairs of mothers and children in the study, including a set of twins. Three groups were infected with HBV genotype C, and six...
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