Article
Evolution and mutations of hepatitis B virus quasispecies in genotype B and C during vertical transmission.
Journal of medical virology - 1 Jun 2016
Wu Quanxin, Xu Cheng, Li Junnan, Li Li, Yan Guohua, Yue Liangliang, Zeng Yi, Huang Hongfei, Deng Guohong, Wang Yuming
Abstract excerpt
Evolution patterns of HBV QS between genotype B and C during vertical transmission are not well understood. In this study, we enrolled 10 HBV infected mother-infant pairs (four pairs with genotype B, four pairs with genotype C, and two with co-infection) without anti-viral therapy. Serum HBV DNA of mothers and infants were sequenced, HBV QS complexity and diversity were analyzed, polymorphisms and mutation sites...
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