Article
Evolution of hepatitis B genotype C viral quasi-species during hepatitis B e antigen seroconversion.
Journal of hepatology - 1 Jan 2011
Wu Shuang, Imazeki Fumio, Kurbanov Fuat, Fukai Kenichi, Arai Makoto, Kanda Tatsuo, Yonemitsu Yutaka, Tanaka Yasuhito, Mizokami Masashi, Yokosuka Osamu
Abstract excerpt
BACKGROUND & AIMS: Although the evolution of viral quasi-species may be related to the pathological status of disease, little is known about this phenomenon in hepatitis B, particularly with respect to hepatitis B e antigen (HBeAg) seroconversion. METHODS: Nucleotide sequences of the hepatitis B virus (HBV) X/precore/core region was analyzed at five time-points in four groups of chronic hepatitis B patients,...
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