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Article

Quasispecies characteristics in mother-to-child transmission of hepatitis B virus by next-generation sequencing.

The Journal of infection - 1 Jul 2017

Yang Guifeng, Liu Zhihua, Yang Juncheng, Luo Kangxian, Xu Ying, He Haitang, Fu Qunfang, Yu Shouyi, Wang Zhanhui

Abstract excerpt

OBJECTIVES: To identify within-host quasispecies characteristics of hepatitis B virus (HBV) in mothers and children infected via mother-to-child transmission (MTCT). METHODS: Using next-generation sequencing (NGS), we analyzed sequences within the non-overlapping pre-core/core (pre-C/C) gene in 37 mother-child pairs. RESULTS: Phylogenetic and Highlighter analyses suggested that both a single strain and multiple...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28483405
DOI: 10.1016/j.jinf.2017.04.012

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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