The role of OPRM1 polymorphism in the etiology of alcoholism.

doi:10.17219/acem/78592

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

The role of OPRM1 polymorphism in the etiology of alcoholism.

Advances in clinical and experimental medicine : official organ Wroclaw Medical University - 1 Feb 2019

Samochowiec Agnieszka, Samochowiec Jerzy, Pełka-Wysiecka Justyna, Kucharska-Mazur Jolanta, Grochans Elżbieta, Jabłoński Marcin, Bieńkowski Przemysław, Murawiec Sławomir, Małecka Iwona, Mak Monika, Kołodziej Łukasz, Heitzman Janusz, Grzywacz Anna

Abstract excerpt

BACKGROUND: Numerous studies have investigated the association between the OPRM1 A118G polymorphism (rs1799971) and alcohol dependence, but the results have been inconsistent. The endogenous opioid system has been implicated in the development of alcohol dependence for its prominent role in the central rewarding mechanism. OBJECTIVES: The aim of this study was to evaluate the role of the A118G polymorphism of the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Receptors, Opioid, mu

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Alcoholism

Share to Alleles

Share to Case-Control Studies

Share to OPRM1 gene

Share to Genotype

Share to Polymorphism, Genetic

Share to Polymorphism, Single Nucleotide

Source

Open in PubMed

Identifiers

PMID: 30085428
DOI: 10.17219/acem/78592

Genes

OPRM1

Variants

rs1799971

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The role of OPRM1 polymorphism in the etiology of alcoholism.PMID 30085428Read ↗

Possible association between OPRM1 genetic variance at the 118 locus and alcohol dependence in a large treatment sample: relationship to alcohol dependence symptoms.Semantic proximity Read ↗

Lack of associations of the opioid receptor mu 1 (OPRM1) A118G polymorphism (rs1799971) with alcohol dependence: review and meta-analysis of retrospective controlled studies.Semantic proximity Read ↗

Influence of the OPRM1 A118G polymorphism on alcohol-induced euphoria, risk for alcoholism and the clinical efficacy of naltrexone.Semantic proximity Read ↗

[μ-Opioid Receptor Gene (OPRM1) Polymorphisms A118G and C17T in Alcohol Dependence: A Turkish Sample].Semantic proximity Read ↗

Association of µ-opioid receptor (OPRM1) gene polymorphism with response to naltrexone in alcohol dependence: a systematic review and meta-analysis.Semantic proximity Read ↗

The OPRM1 A118G polymorphism: converging evidence against associations with alcohol sensitivity and consumption.Semantic proximity Read ↗

Polymorphisms in the mu-opioid receptor gene (OPRM1) and the implications for alcohol dependence in humans.Semantic proximity Read ↗

Increased attributable risk related to a functional mu-opioid receptor gene polymorphism in association with alcohol dependence in central Sweden.Semantic proximity Read ↗

Association of functional opioid receptor genotypes with alcohol dependence in Koreans.Semantic proximity Read ↗

Association of mu-opioid receptor gene polymorphism A118G with alcohol dependence in a Japanese population.Semantic proximity Read ↗

A polymorphism of the mu-opioid receptor gene (OPRM1) and sensitivity to the effects of alcohol in humans.Semantic proximity Read ↗

Single-nucleotide polymorphism (A118G) in exon 1 of OPRM1 gene causes alteration in downstream signaling by mu-opioid receptor and may contribute to the genetic risk for addiction.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.