Article
[μ-Opioid Receptor Gene (OPRM1) Polymorphisms A118G and C17T in Alcohol Dependence: A Turkish Sample].
Turk psikiyatri dergisi = Turkish journal of psychiatry - 1 Jan 2016
Gürel Şeref Can, Ayhan Yavuz, Karaaslan Çağatay, Akel Hayriye, Karaca Ragıp Özgür, Babaoğlu Melih Önder, Yaşar Ümit, Bozkurt Atilla, Dilbaz Nesrin, Uluğ Berna Diclenur, Demir Başaran
Abstract excerpt
OBJECTIVES: Previous investigations on opioid system genetics have identified polymorphisms of the OPRM1 gene expressing μ-opioid receptors to be significantly associated with some features of alcohol dependence (AD). In the present study, we evaluated the relationship between single nucleotide polymorphisms (SNP) in the OPRM1 gene, A118G (rs1799971, Asn40Asp) and C17T (rs1799972, Arg6Val), and AD diagnosis,...
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