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Article

Analysis of KRAS, NRAS, BRAF, and PIK3CA mutations could predict metastases in colorectal cancer: A preliminary study.

Advances in clinical and experimental medicine : official organ Wroclaw Medical University - 1 Jan 2019

Wojas-Krawczyk Kamila, Kalinka-Warzocha Ewa, Reszka Katarzyna, Nicoś Marcin, Szumiło Justyna, Mańdziuk Sławomir, Szczepaniak Katarzyna, Kupnicka Dorota, Lewandowski Remigiusz, Milanowski Janusz, Krawczyk Paweł

Abstract excerpt

BACKGROUND: Colorectal cancer (CRC) is usually diagnosed in the metastatic stage, when chemotherapy and molecularly-targeted therapies, instead of surgery, play the most important therapeutic role. Application of anti-epidermal growth factor receptor (EGFR) therapy requires the analysis of RAS mutation status and only RAS wild-type (wt) patients are qualified for the therapy. OBJECTIVES: The objective of this...

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PMID: 30085422
DOI: 10.17219/acem/76162

Genes

NRAS
BRAF
KRAS
EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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