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Article

Elucidating the prognostic significance of KRAS, NRAS, BRAF and PIK3CA mutations in Chinese patients with metastatic colorectal cancer.

Asia-Pacific journal of clinical oncology - 1 Jun 2015

Ma Brigette B, Mo Frankie, Tong Joanna H, Wong Ashley, Wong S C Cesar, Ho Wing M, Wu Cherry, Lam Polly W Y, Chan K F, Chan Timothy S K, Tsui Wilson M S, Tsang Alex K H, Fung Mandy N S, Chan Anthony T C, To Ka Fai

Abstract excerpt

AIM: The prognostic significance of KRAS, NRAS, PIK3CA and BRAF mutations was evaluated in Chinese patients with metastatic colorectal cancer (CRC). METHOD: Tumor samples from 183 patients were retrospectively tested for KRAS, NRAS, PIK3CA and BRAF mutations. Multivariate analysis was performed t...

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Identifiers

PMID: 25865669
DOI: 10.1111/ajco.12342

Genes

KRAS
BRAF
NRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25865669-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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