Article
Loss of miR-146b-3p Inhibits Perivascular Adipocyte Browning with Cold Exposure During Aging.
Cardiovascular drugs and therapy - 1 Oct 2018
Pan Xiao-Xi, Cao Jiu-Mei, Cai Fan, Ruan Cheng-Chao, Wu Fang, Gao Ping-Jin
Abstract excerpt
PURPOSE: Pathological changes of the perivascular adipose tissue (PVAT) are directly associated with increased risk of age-related vascular diseases. MicroRNAs regulate adipocyte biological functions including adipogenic differentiation and white adipocyte browning. The present study aims to determine whether miR-146b-3p is involved in the regulation of perivascular adipocyte browning during aging. METHODS: We...
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