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Article

Aging impairs cold-induced beige adipogenesis and adipocyte metabolic reprogramming

31 May 2023

Abstract excerpt

The energy-burning capability of beige adipose tissue is a potential therapeutic tool for reducing obesity and metabolic disease, but this capacity is decreased by aging. Here, we evaluate the impact of aging on the profile and activity of adipocyte stem and progenitor cells (ASPCs) and adipocytes during the beiging process in mice. We found that aging increases the expression of Cd9 and other fibro-inflammatory...

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Share to Adipokines, Inflammation, and Metabolic Diseases
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Identifiers

PMID: 38775132
DOI: 10.7554/elife.87756

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