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Article

The role of microRNA-23b-5p in regulating brown adipogenesis and thermogenic program

1 May 2020

Abstract excerpt

Enhanced brown adipose tissue (BAT) mass and activity have been demonstrated to promote the expenditure of excess stored energy and reduce prevalence of obesity. Cold is known as a potent stimulator of BAT and activates BAT primarily through the β3-adrenergic-cAMP signaling. Here, we performed RNA-sequencing to identify differential miRNAs in mouse BAT upon cold exposure and a total of 20 miRNAs were validated....

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Share to Adipokines, Inflammation, and Metabolic Diseases
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PMID: 32348962
DOI: 10.1530/ec-20-0124

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