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Article

Cellular Aging Contributes to Failure of Cold-Induced Beige Adipocyte Formation in Old Mice and Humans.

Cell metabolism - 10 Jan 2017

Berry Daniel C, Jiang Yuwei, Arpke Robert W, Close Elizabeth L, Uchida Aki, Reading David, Berglund Eric D, Kyba Michael, Graff Jonathan M

Abstract excerpt

Cold temperatures induce progenitor cells within white adipose tissue to form beige adipocytes that burn energy and generate heat; this is a potential anti-diabesity therapy. However, the potential to form cold-induced beige adipocytes declines with age. This creates a clinical roadblock to poten...

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Identifiers

PMID: 27889388
DOI: 10.1016/j.cmet.2016.10.023
PMCID: PMC5226893

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Prepared record publication-27889388-2026-09-05.1. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 5 Sept 2026.

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Cellular Aging Contributes to Failure of Cold-Induced Beige Adipocyte Formation in Old Mice and Humans.PMID 27889388Read ↗

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