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MicroRNAs Are Required for the Feature Maintenance and Differentiation of Brown Adipocytes

10 Jul 2014

Abstract excerpt

Brown adipose tissue (BAT) is specialized to burn lipids for heat generation as a natural defense against cold and obesity. Previous studies established microRNAs (miRNAs) as essential regulators of brown adipocyte differentiation, but whether miRNAs are required for the feature maintenance of mature brown adipocytes remains unknown. To address this question, we ablated Dgcr8, a key regulator of the miRNA...

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Share to Adipose Tissue and Metabolism
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 25008181
DOI: 10.2337/db14-0466

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