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Article

Evaluation of serum sphingolipids and the influence of genetic risk factors in age-related macular degeneration.

PloS one - 1 Jan 2018

Pujol-Lereis Luciana M, Liebisch Gerhard, Schick Tina, Lin Yuchen, Grassmann Felix, Uchida Koji, Zipfel Peter F, Fauser Sascha, Skerka Christine, Weber Bernhard H F

Abstract excerpt

Sphingolipids are bioactive molecules associated with oxidative stress, inflammation, and neurodegenerative diseases, but poorly studied in the context of age-related macular degeneration (AMD), a prevalent sight-threatening disease of the ageing retina. Here, we found higher serum levels of hexosylceramide (HexCer) d18:1/16:0 in patients with choroidal neovascularization (CNV) and geographic atrophy (GA), two...

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Identifiers

PMID: 30071029
DOI: 10.1371/journal.pone.0200739
PMCID: PMC6071970

Genes

CFH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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