Analysis of complement factor H Y402H, LOC387715, HTRA1 polymorphisms and ApoE alleles with susceptibility to age-related macular degeneration in Hungarian patients.

doi:10.1111/j.1755-3768.2009.01687.x

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Analysis of complement factor H Y402H, LOC387715, HTRA1 polymorphisms and ApoE alleles with susceptibility to age-related macular degeneration in Hungarian patients.

Acta ophthalmologica - 1 May 2011

Losonczy Gergely, Fekete Ágnes, Vokó Zoltán, Takács Lili, Káldi Ildikó, Ajzner Éva, Kasza Márta, Vajas Attila, Berta András, Balogh István

Abstract excerpt

PURPOSE: Recent studies strongly support the role of genetic factors in the aetiology of age-related macular degeneration (AMD). We investigated the frequency of Tyr402His polymorphism of the complement factor H (CFH) gene, Ser69Ala polymorphism at LOC387715, rs11200638 polymorphism of the HTRA1 gene and different apolipoprotein E (ApoE) alleles in Hungarian patients with AMD in order to determine the disease...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Apolipoproteins E

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Complement Factor H

Share to High-Temperature Requirement A Serine Peptidase 1

Share to Hungary

Share to Macular Degeneration

Share to Odds Ratio

Share to Serine Endopeptidases

Share to Surveys and Questionnaires

Source

Open in PubMed

Identifiers

PMID: 19845562
DOI: 10.1111/j.1755-3768.2009.01687.x

Genes

CFH
HTRA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Analysis of complement factor H Y402H, LOC387715, HTRA1 polymorphisms and ApoE alleles with susceptibility to age-related macular degeneration in Hungarian patients.PMID 19845562Read ↗

Complement factor H and LOC387715 gene polymorphisms in a Greek population with age-related macular degeneration.Semantic proximity Read ↗

LOC387715/HTRA1 and complement factor H variants in patients with age-related macular degeneration seen at the mayo clinic.Semantic proximity Read ↗

Association of CFH, LOC387715, and HTRA1 polymorphisms with exudative age-related macular degeneration in a northern Chinese population.Semantic proximity Read ↗

Neovascular age-related macular degeneration and its association with LOC387715 and complement factor H polymorphism.Semantic proximity Read ↗

Hypothetical LOC387715 is a second major susceptibility gene for age-related macular degeneration, contributing independently of complement factor H to disease risk.Semantic proximity Read ↗

An update on the genetics of age-related macular degenerationSemantic proximity Read ↗

Effect of the Gas6 c.834+7G>A polymorphism and the interaction of known risk factors on AMD pathogenesis in Hungarian patients.Semantic proximity Read ↗

Multifactor effects and evidence of potential interaction between complement factor H Y402H and LOC387715 A69S in age-related macular degeneration.Semantic proximity Read ↗

Comprehensive analysis of complement factor H and LOC387715/ARMS2/HTRA1 variants with respect to phenotype in advanced age-related macular degeneration.Semantic proximity Read ↗

Complement Factor H Polymorphism, Complement Activators, and Risk of Age-Related Macular DegenerationSemantic proximity Read ↗

LOC387715/HTRA1 polymorphisms, smoking and combined effects on exudative age-related macular degeneration in a Korean population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.