Article
Analysis of variants in the complement factor H, the elongation of very long chain fatty acids-like 4 and the hemicentin 1 genes of age-related macular degeneration in the Finnish population.
Molecular vision - 20 Jul 2006
Seitsonen Sanna, Lemmelä Susanna, Holopainen Juha, Tommila Petri, Ranta Päivi, Kotamies Antti, Moilanen Jukka, Palosaari Tapani, Kaarniranta Kai, Meri Seppo, Immonen Ilkka, Järvelä Irma
Abstract excerpt
PURPOSE: A strong association of a Tyr402His polymorphism in the complement factor H (CFH) gene and a Met299Val polymorphism in the elongation of very long chain fatty acids-like 4 (ELOVL4) gene with age-related macular degeneration (AMD) has been identified in Caucasian populations in the United States. Earlier a Gln5345Arg variant in the hemicentin 1 (HMCN1) gene was reported in a large AMD family in the United...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.