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An update on the genetics of age-related macular degeneration

1 Jan 2007

Abstract excerpt

Age-related macular degeneration (AMD) is a genetically complex disorder of the photoreceptor-RPE-Bruch's membrane-choriocapillaris complex. Family and twin studies have shown that the susceptibility for this disease is genetically influenced. The heritability has been estimated to be up to 71%. Linkage and association studies have identified several chromosomal regions that are likely to contain susceptibility...

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PMID: 17327825
DOI: 10.5283/epub.35844

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