Article
Fine tuning the level of the Cdc13 telomere-capping protein for maximal chromosome stability performance.
Current genetics - 1 Feb 2019
Mersaoui Sofiane Y, Wellinger Raymund J
Abstract excerpt
Chromosome stability relies on an adequate length and complete replication of telomeres, the physical ends of chromosomes. Telomeres are composed of short direct repeat DNA and the associated nucleoprotein complex is essential for providing end-stability. In addition, the so-called end-replication problem of the conventional replication requires that telomeres be elongated by a special mechanism which, in...
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