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Article

Bring It to an End: Does Telomeres Size Matter?

8 Jan 2019

Abstract excerpt

Telomeres are unique nucleoprotein structures. Found at the edge of each chromosome, their main purpose is to mask DNA ends from the DNA-repair machinery by formation of protective loops. Through life and cell divisions, telomeres shorten and bring cells closer to either cell proliferation crisis or senescence. Beyond this mitotic clock role attributed to the need for telomere to be maintained over a critical...

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PMID: 30626097
DOI: 10.3390/cells8010030

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