Article
Structural identity of telomeric complexes.
FEBS letters - 10 Sept 2010
Giraud-Panis Marie-Josèphe, Pisano Sabrina, Poulet Anaïs, Le Du Marie-Hélène, Gilson Eric
Abstract excerpt
A major issue in telomere research is to understand how the integrity of chromosome ends is controlled. Although several nucleoprotein complexes have been described at the telomeres of different organisms, it is still unclear how they confer a structural identity to chromosome ends in order to mask them from DNA repair and to ensure their proper replication. In this review, we describe how telomeric nucleoprotein...
Topics
- Animals
- DNA
- DNA Repair
- Genetic Variation
- Humans
- Mammals
- Oxytricha
- Proteins
- RNA
- Saccharomyces cerevisiae
- Schizosaccharomyces
- Tandem Repeat Sequences
- Telomere
