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Chromosome ends: different sequences may provide conserved functions

13 Jun 2005

Abstract excerpt

The structures of specific chromosome regions, centromeres and telomeres, present a number of puzzles. As functions performed by these regions are ubiquitous and essential, their DNA, proteins and chromatin structure are expected to be conserved. Recent studies of centromeric DNA from human, Drosophila and plant species have demonstrated that a hidden universal centromere-specific sequence is highly unlikely. The...

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PMID: 15954099
DOI: 10.1002/bies.20259

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