Article

Unravelling the Intricacies of Telomere Replication: A Molecular Conundrum

2023-12-22

Abstract excerpt

Telomeres are specialized structures at the ends of linear chromosomes that protect them from degradation and fusion. Telomere replication is a complex process that involves both DNA polymerases and a specialized enzyme called telomerase. Telomerase is a ribonucleoprotein complex that synthesizes telomeric DNA by using an internal RNA template. However, telomerase alone cannot fully replicate the telomeric DNA, an...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 56713423-667b-509e-a7aa-308854b0f0ad
DOI: 10.20944/preprints202312.1720.v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Unravelling the Intricacies of Telomere Replication: A Molecular ConundrumDOI 10.20944/preprints202312.1720.v1Read

Telomeres and telomerase.Semantic proximity Read

Telomeres and CancerSemantic proximity Read

Chromosome End Maintenance by TelomeraseSemantic proximity Read

Role of Telomeres and Telomeric Proteins in Human Malignancies and Their Therapeutic PotentialSemantic proximity Read

Telomere Maintenance and DNA Repair: A Bidirectional Relationship in Cancer Biology and TherapySemantic proximity Read

The human telomere and its relationship to human disease, therapy, and tissue engineering.Semantic proximity Read

Telomeres, aging and cancer: in search of a happy ending.Semantic proximity Read

Telomere shortening in human diseasesSemantic proximity Read

Telomeres, telomerase and senescence.Semantic proximity Read

Loss of Telomere Protection: Consequences and OpportunitiesSemantic proximity Read

Telomeres, chromosome instability and cancerSemantic proximity Read

Telomeres and Telomere Length: A General OverviewSemantic proximity Read