Article
WISH-R- a fast and efficient tool for construction of epistatic networks for complex traits and diseases.
BMC bioinformatics - 31 Jul 2018
Carmelo Victor A O, Kogelman Lisette J A, Madsen Majbritt Busk, Kadarmideen Haja N
Abstract excerpt
BACKGROUND: Genetic epistasis is an often-overlooked area in the study of the genomics of complex traits. Genome-wide association studies are a useful tool for revealing potential causal genetic variants, but in this context, epistasis is generally ignored. Data complexity and interpretation issues make it difficult to process and interpret epistasis. As the number of interaction grows exponentially with the...
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