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Article

Vaccinia-related kinase 2 modulates role of dysbindin by regulating protein stability.

Journal of neurochemistry - 1 Dec 2018

Jeong Young-Hun, Choi Jung-Hyun, Lee Dohyun, Kim Sangjune, Kim Kyong-Tai

Abstract excerpt

Vaccinia-related kinase 2 (VRK2) is a serine/threonine kinase that belongs to the casein kinase 1 family. VRK2 has long been known for its relationship with neurodegenerative disorders such as schizophrenia. However, the role of VRK2 and the substrates associated with it are unknown. Dysbindin is known as one of the strong risk factors for schizophrenia. The expression of dysbindin is indeed significantly reduced...

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Source

Identifiers

PMID: 30062698
DOI: 10.1111/jnc.14562

Genes

VRK2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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