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Article

Mutation of the protein kinase C site in borna disease virus phosphoprotein abrogates viral interference with neuronal signaling and restores normal synaptic activity.

PLoS pathogens - 1 May 2009

Prat Christine M A, Schmid Sonja, Farrugia Fanny, Cenac Nicolas, Le Masson Gwendal, Schwemmle Martin, Gonzalez-Dunia Daniel

Abstract excerpt

Understanding the pathogenesis of infection by neurotropic viruses represents a major challenge and may improve our knowledge of many human neurological diseases for which viruses are thought to play a role. Borna disease virus (BDV) represents an attractive model system to analyze the molecular mechanisms whereby a virus can persist in the central nervous system (CNS) and lead to altered brain function, in the...

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Identifiers

PMID: 19424436
DOI: 10.1371/journal.ppat.1000425
PMCID: PMC2673689

Genes

MARCKS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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