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Article

Proteome and behavioral alterations in phosphorylation-deficient mutant Collapsin Response Mediator Protein2 knock-in mice.

Neurochemistry international - 1 Oct 2018

Nakamura Haruko, Takahashi-Jitsuki Aoi, Makihara Hiroko, Asano Tetsuya, Kimura Yayoi, Nakabayashi Jun, Yamashita Naoya, Kawamoto Yuko, Nakamura Fumio, Ohshima Toshio, Hirano Hisashi, Tanaka Fumiaki, Goshima Yoshio

Abstract excerpt

CRMP2, alternatively designated as DPYSL2, was the first CRMP family member to be identified as an intracellular molecule mediating the signaling of the axon guidance molecule Semaphorin 3A (Sema3A). In Sema3A signaling, cyclin-dependent kinase 5 (Cdk5) primarily phosphorylates CRMP2 at Ser522. Glycogen synthase kinase-3β (GSK-3β) subsequently phosphorylates the residues of Thr509 and Thr514 of CRMP2. Previous...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 29758318
DOI: 10.1016/j.neuint.2018.04.009

Genes

DPYSL2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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