Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Vaccinia Related Kinase 2 (VRK2) expression in neurological disorders: schizophrenia, epilepsy and multiple sclerosis.

Multiple sclerosis and related disorders - 1 Jan 2018

Azimi Tahereh, Ghafouri-Fard Soudeh, Davood Omrani Mir, Mazdeh Mehrdokht, Arsang-Jang Shahram, Sayad Arezou, Taheri Mohammad

Abstract excerpt

BACKGROUND: Schizophrenia (SCZ), epilepsy and Multiple Sclerosis (MS) are neurological disorders with increasing prevalence disturb the patients' lives and are regarded as burdens to the society. As multifactorial disorders, genetic susceptibility factors are involved in their pathogenesis. The Vaccinia-Related Kinase 2 (VRK2) gene codes for a serine threonine kinase recently reported to be contributed in the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Down-Regulation
Share to Epilepsy

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression

Share to Multiple Sclerosis

Share to Protein Serine-Threonine Kinases

Share to RNA, Messenger

Share to Schizophrenia

Share to Signal Transduction

Source

Identifiers

PMID: 29100046
DOI: 10.1016/j.msard.2017.10.017

Genes

VRK2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Vaccinia Related Kinase 2 (VRK2) expression in neurological disorders: schizophrenia, epilepsy and multiple sclerosis.PMID 29100046Read ↗

VRK2 gene expression in schizophrenia, bipolar disorder and healthy controls.Semantic proximity Read ↗

Association of the VRK2 gene rs3732136 polymorphism with schizophrenia in a Northwest Chinese Han population.Semantic proximity Read ↗

Vaccinia-related kinase 2 modulates role of dysbindin by regulating protein stability.Semantic proximity Read ↗

Meta-analysis and brain imaging data support the involvement of VRK2 (rs2312147) in schizophrenia susceptibility.Semantic proximity Read ↗

Common variants at VRK2 and TCF4 conferring risk of schizophrenia.Semantic proximity Read ↗

Reduced Vrk2 expression is associated with higher risk of depression in humans and mediates depressive-like behaviors in mice.Semantic proximity Read ↗

CPEB1, a novel risk gene in recent-onset schizophrenia, contributes to mitochondrial complex I defect caused by a defective provirus ERVWE1Semantic proximity Read ↗

Further evidence of VRK2 rs2312147 associated with schizophrenia.Semantic proximity Read ↗

GWAS Identifies Candidate Susceptibility Loci and Microrna Biomarkers for Acute Encephalopathy with Biphasic Seizures and Late Reduced DiffusionSemantic proximity Read ↗

High risk genotypes for schizophrenia may have been adaptive in the context of smallpox.Semantic proximity Read ↗

A novel mechanism to explain protein abnormalities in schizophrenia based on the flavivirus resistance gene.Semantic proximity Read ↗

[Replicative study of susceptibility to childhood-onset schizophrenia in Kazakhs].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.