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Article

Mutations in the Drosophila tricellular junction protein M6 synergize with RasV12 to induce apical cell delamination and invasion.

Proceedings of the National Academy of Sciences of the United States of America - 14 Aug 2018

Dunn Brandon S, Rush Lindsay, Lu Jin-Yu, Xu Tian

Abstract excerpt

Complications from metastasis are responsible for the majority of cancer-related deaths. Despite the outsized medical impact of metastasis, remarkably little is known about one of the key early steps of metastasis: departure of a tumor cell from its originating tissue. It is well documented that cellular delamination in the basal direction can induce invasive behaviors, but it remains unknown if apical cell...

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Identifiers

PMID: 30061406
DOI: 10.1073/pnas.1807343115
PMCID: PMC6099892

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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