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Article

Mitochondrial localization and the persistent migration of epithelial cancer cells.

Biophysical journal - 7 May 2013

Desai Salil P, Bhatia Sangeeta N, Toner Mehmet, Irimia Daniel

Abstract excerpt

During cancer cell invasion, faster moving cancer cells play a dominant role by invading further and metastasizing earlier. Despite the importance of these outlier cells, the source of heterogeneity in their migratory behavior remains poorly understood. Here, we show that anterior localization of mitochondria, in between the nucleus and the leading edge of migrating epithelial cancer cells, correlates with faster...

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Identifiers

PMID: 23663851
DOI: 10.1016/j.bpj.2013.03.025
PMCID: PMC3647149

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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