Article
Overexpression of FGFR3 in HPV-positive Tonsillar and Base of Tongue Cancer Is Correlated to Outcome.
Anticancer research - 1 Aug 2018
Bersani Cinzia, Haeggblom Linnea, Ursu Ramona G, Giusca Simona E, Marklund Linda, Ramqvist Torbjörn, Näsman Anders, Dalianis Tina
Abstract excerpt
BACKGROUND/AIM: Human papillomavirus-positive (HPV+) tonsillar and base of tongue squamous cell carcinoma (TSCC/BOTSCC) have better outcome than corresponding HPV- cancers. To better individualize treatment, additional predictive markers are needed. Previously, we have shown that mutated fibroblast growth factor receptor 3 protein (FGFR3) was correlated to poorer prognosis and here FGFR3 expression was further...
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