Article
A high and increasing HPV prevalence in tonsillar cancers in Eastern Denmark, 2000-2010: the largest registry-based study to date.
International journal of cancer - 1 May 2015
Garnaes Emilie, Kiss Katalin, Andersen Luise, Therkildsen Marianne H, Franzmann Maria B, Filtenborg-Barnkob Bettina, Hoegdall Estrid, Krenk Lene, Josiassen Michael, Lajer Christel B, Specht Lena, Frederiksen Kirsten, Friis-Hansen Lennart, Nielsen Finn C, Kjaer Susanne K, Norrild Bodil, von Buchwald Christian
Abstract excerpt
The aim was to explore whether the incidence of tonsillar squamous cell carcinomas (TSCCs) increased in Eastern Denmark, 2000-2010, and whether human papillomavirus (HPV) could explain the increase, and to assess the association of HPV prevalence with gender, age, and origin (i.e., the certainty of tonsillar tumor origin). We applied HPV DNA PCR and p16 immunohistochemistry to all TSCCs registered in the Danish...
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