Article
Targeted sequencing of tonsillar and base of tongue cancer and human papillomavirus positive unknown primary of the head and neck reveals prognostic effects of mutated FGFR3.
Oncotarget - 23 May 2017
Bersani Cinzia, Sivars Lars, Haeggblom Linnea, DiLorenzo Sebastian, Mints Michael, Ährlund-Richter Andreas, Tertipis Nikolaos, Munck-Wikland Eva, Näsman Anders, Ramqvist Torbjörn, Dalianis Tina
Abstract excerpt
BACKGROUND: Human papillomavirus positive (HPV+) tonsillar cancer (TSCC), base of tongue cancer (BOTSCC) and unknown primary cancer of the head and neck (HNCUP) have better outcome than corresponding HPV- cancers. To find predictive markers for response to treatment, and correlations and differences in mutated oncogenes and suppressor genes between HPV+ TSCC/BOTSSCC and HPV+ HNCUP and HPV- TSCC/BOTSCC targeted...
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