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Article

Vulvar Squamous Cell Carcinoma (VSCC) as Two Diseases: HPV Status Identifies Distinct Mutational Profiles Including Oncogenic Fibroblast Growth Factor Receptor 3.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Aug 2017

Weberpals Johanne I, Lo Bryan, Duciaume Marc M, Spaans Johanna N, Clancy Aisling A, Dimitroulakos Jim, Goss Glenwood D, Sekhon Harman S

Abstract excerpt

Purpose: Patients with advanced or recurrent invasive vulvar squamous cell carcinoma (VSCC) have limited treatment options and a grave prognosis. Understanding the genomic landscape may facilitate the identification of new therapies and improve clinical outcomes.Experimental Design: A retrospective chart review and molecular analysis of patients with VSCC from 2000 to 2016 was performed at the Ottawa Hospital...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28377483
DOI: 10.1158/1078-0432.CCR-16-3230

Genes

FGFR3
HRAS
PTEN

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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