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Article

Fibroblast growth factor receptor (FGFR) alterations in squamous differentiated bladder cancer: a putative therapeutic target for a small subgroup.

Oncotarget - 1 Nov 2016

Baldia Philipp H, Maurer Angela, Heide Timon, Rose Michael, Stoehr Robert, Hartmann Arndt, Williams Sarah V, Knowles Margaret A, Knuechel Ruth, Gaisa Nadine T

Abstract excerpt

Although drugable fibroblast growth factor receptor (FGFR) alterations in squamous cell carcinomas (SCC) of various entities are well known, little is known about FGFR modifications in squamous differentiated bladder cancer. Therefore, our study evaluated FGFR1-3 alterations as a putative therapeutic target in this subgroup. We analyzed 73 squamous differentiated bladder cancers (n = 10 pT2, n = 55 pT3, n = 8...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27669755
DOI: 10.18632/oncotarget.12198
PMCID: PMC5342089

Genes

FGFR3
FGFR1
FGFR2
TACC3

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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