Article
Protein Expression in Tonsillar and Base of Tongue Cancer and in Relation to Human Papillomavirus (HPV) and Clinical Outcome.
International journal of molecular sciences - 25 Mar 2018
Ramqvist Torbjörn, Näsman Anders, Franzén Bo, Bersani Cinzia, Alexeyenko Andrey, Becker Susanne, Haeggblom Linnea, Kolev Aeneas, Dalianis Tina, Munck-Wikland Eva
Abstract excerpt
Human papillomavirus (HPV) is a major etiological factor for tonsillar and the base of tongue cancer (TSCC/BOTSCC). HPV-positive and HPV-negative TSCC/BOTSCC present major differences in mutations, mRNA expression and clinical outcome. Earlier protein studies on TSCC/BOTSCC have mainly analyzed individual proteins. Here, the aim was to compare a larger set of cancer and immune related proteins in HPV-positive and...
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