Article
Polymorphisms in the DAD1 and OXA1L genes are associated with asthma and atopy in a South American population.
Molecular immunology - 1 Sept 2018
Pires Anaque de Oliveira, Queiroz Gerson de Almeida, de Jesus Silva Milca, da Silva Raimon Rios, da Silva Hugo Bernardino Ferreira, Carneiro Norma Vilany Queiroz, Fonseca Héllen Freitas, de Santana Maria Borges Rabelo, Nascimento Regina Santos, Alcântara-Neves Neuza Maria, Costa Gustavo Nunes de Oliveira, Costa Ryan Dos Santos, Barreto Maurício L, Figueiredo Camila Alexandrina
Abstract excerpt
Atopic asthma, which is characterized by the chronic inflammation and morbidity of airways, is a disease of great complexity, and multiple genetic and environmental factors are involved in its etiology. In the first genome-wide association study (GWAS) conducted in Brazil for asthma, a positive association was found between atopic asthma and a variant (rs1999071), which is located between the DAD1 and OXA1L...
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