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New variants of the DAD1 and OXA1L genes are associated with asthma and atopy in an adult population.

Gene - 10 Feb 2025

Pires Anaque O, de Lima Louise C, de Andrade Candace M, Coelho Raísa S, Silva Hátilla Dos S, Queiroz Gerson A, Fernandes Jamille, Pinheiro Gabriela P, Cruz Álvaro A, Costa Ryan Dos S, Figueiredo Camila A V

Abstract excerpt

Asthma is a complex disease characterized by reversible and intermittent airway obstruction that has shown a high prevalence and unacceptable mortality in adults. In recent years, several genome-wide association studies (GWAS) have identified variants linked to asthma susceptibility. The DAD1 gene is known for regulating programmed cell death, and OXA1L is described for its involvement in mitochondrial biogenesis...

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PMID: 39615807
DOI: 10.1016/j.gene.2024.149124

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