Article
Genome-wide association study identifies PERLD1 as asthma candidate gene.
BMC medical genetics - 21 Dec 2011
Anantharaman Ramani, Andiappan Anand Kumar, Nilkanth Pallavi Parate, Suri Bani Kaur, Wang De Yun, Chew Fook Tim
Abstract excerpt
BACKGROUND: Recent genome-wide association studies (GWAS) for asthma have been successful in identifying novel associations which have been well replicated. The aim of this study is to identify the genetic variants that influence predisposition towards asthma in an ethnic Chinese population in Singapore using a GWAS approach. METHODS: A two-stage GWAS was performed in case samples with allergic asthma, and in...
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