Article
A genome-wide association study of asthma symptoms in Latin American children.
BMC genetics - 3 Dec 2015
Costa Gustavo N O, Dudbridge Frank, Fiaccone Rosemeire L, da Silva Thiago M, Conceição Jackson S, Strina Agostino, Figueiredo Camila A, Magalhães Wagner C S, Rodrigues Maira R, Gouveia Mateus H, Kehdy Fernanda S G, Horimoto Andrea R V R, Horta Bernardo, Burchard Esteban G, Pino-Yanes Maria, Del Rio Navarro Blanca, Romieu Isabelle, Hancock Dana B, London Stephanie, Lima-Costa Maria Fernanda, Pereira Alexandre C, Tarazona Eduardo, Rodrigues Laura C, Barreto Mauricio L
Abstract excerpt
BACKGROUND: Asthma is a chronic disease of the airways and, despite the advances in the knowledge of associated genetic regions in recent years, their mechanisms have yet to be explored. Several genome-wide association studies have been carried out in recent years, but none of these have involved Latin American populations with a high level of miscegenation, as is seen in the Brazilian population. METHODS: 1246...
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