Variants of DENND1B associated with asthma in children.

doi:10.1056/NEJMoa0901867

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Article

Variants of DENND1B associated with asthma in children.

The New England journal of medicine - 7 Jan 2010

Sleiman Patrick M A, Flory James, Imielinski Marcin, Bradfield Jonathan P, Annaiah Kiran, Willis-Owen Saffron A G, Wang Kai, Rafaels Nicholas M, Michel Sven, Bonnelykke Klaus, Zhang Haitao, Kim Cecilia E, Frackelton Edward C, Glessner Joseph T, Hou Cuiping, Otieno F George, Santa Erin, Thomas Kelly, Smith Ryan M, Glaberson Wendy R, Garris Maria, Chiavacci Rosetta M, Beaty Terri H, Ruczinski Ingo, Orange Jordan S, Orange Jordan M, Allen Julian, Spergel Jonathan M, Grundmeier Robert, Mathias Rasika A, Christie Jason D, von Mutius Erika, Cookson William O C, Kabesch Michael, Moffatt Miriam F, Grunstein Michael M, Barnes Kathleen C, Devoto Marcella, Magnusson Mark, Li Hongzhe, Grant Struan F A, Bisgaard Hans, Hakonarson Hakon

Abstract excerpt

BACKGROUND: Asthma is a complex disease that has genetic and environmental causes. The genetic factors associated with susceptibility to asthma remain largely unknown. METHODS: We carried out a genomewide association study involving children with asthma. The sample included 793 North American chi...

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PMID: 20032318
DOI: 10.1056/NEJMoa0901867

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20032318-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

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