Article
Adenylyl cyclase type 9 gene polymorphisms are associated with asthma and allergy in Brazilian children.
Molecular immunology - 1 Feb 2017
Teixeira Helena M P, Alcantara-Neves Neuza M, Barreto Maurício, Figueiredo Camila A, Costa Ryan S
Abstract excerpt
Asthma is a chronic inflammatory disease of the respiratory tract. This heterogeneous disease is caused by the interaction of interindividual genetic variability and environmental factors. The gene adenylyl cyclase type 9 (ADCY9) encodes a protein called adenylyl cyclase (AC), responsible for producing the second messenger cyclic AMP (cAMP). cAMP is produced by T regulatory cells and is involved in the...
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